Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha: a role for kupffer cells?

BACKGROUND: It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release mitogenic factors leading to hepatic hyperplasia, and eventually cancer. However, Kupffer cells do not express PPARα receptors, and PPARα agonists stimulate hepatocellular proliferation in...

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Detalles Bibliográficos
Autores principales: Alsarra, Ibrahim A, Brockmann, William G, Cunningham, Michael L, Badr, Mostafa Z
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Short Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1684246/
https://www.ncbi.nlm.nih.gov/pubmed/17129391
http://dx.doi.org/10.1186/1477-3163-5-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1684246/
https://www.ncbi.nlm.nih.gov/pubmed/17129391
http://dx.doi.org/10.1186/1477-3163-5-26

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