17β-Estradiol responsiveness of MCF-7 laboratory strains is dependent on an autocrine signal activating the IGF type I receptor

BACKGROUND: Human MCF-7 cells have been studied extensively as a model for breast cancer cell growth. Many reports have established that serum-starved MCF-7 cells can be induced to proliferate upon the sole addition of 17β-estradiol (E2). However, the extent of the mitogenic response to E2 varies in...

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Detalles Bibliográficos
Autores principales: Hamelers, Irene HL, van Schaik, Richard FMA, Sussenbach, John S, Steenbergh, Paul H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC169177/
https://www.ncbi.nlm.nih.gov/pubmed/12890289
http://dx.doi.org/10.1186/1475-2867-3-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC169177/
https://www.ncbi.nlm.nih.gov/pubmed/12890289
http://dx.doi.org/10.1186/1475-2867-3-10

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