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LRRK2 in Parkinson's disease and dementia with Lewy bodies

BACKGROUND: Mutations in LRRK2 encoding leucine-rich repeat kinase 2 are thus far the most frequent genetic cause associated with autosomal dominant and idiopathic Parkinson's disease (PD). To examine whether LRRK2 is directly associated with neuropathology of PD and other related disorders, we...

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Detalles Bibliográficos
Autores principales: Zhu, Xiongwei, Babar, Asim, Siedlak, Sandra L, Yang, Qiwei, Ito, Genta, Iwatsubo, Takeshi, Smith, Mark A, Perry, George, Chen, Shu G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693553/
https://www.ncbi.nlm.nih.gov/pubmed/17137507
http://dx.doi.org/10.1186/1750-1326-1-17