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PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

Poly(ADP-ribose)polymerase 1 (PARP-1) recognizes DNA strand interruptions in vivo and triggers its own modification as well as that of other proteins by the sequential addition of ADP-ribose to form polymers. This modification causes a release of PARP-1 from DNA ends and initiates a variety of respo...

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Detalles Bibliográficos
Autores principales: Wang, Minli, Wu, Weizhong, Wu, Wenqi, Rosidi, Bustanur, Zhang, Lihua, Wang, Huichen, Iliakis, George
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693894/
https://www.ncbi.nlm.nih.gov/pubmed/17088286
http://dx.doi.org/10.1093/nar/gkl840