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PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
Poly(ADP-ribose)polymerase 1 (PARP-1) recognizes DNA strand interruptions in vivo and triggers its own modification as well as that of other proteins by the sequential addition of ADP-ribose to form polymers. This modification causes a release of PARP-1 from DNA ends and initiates a variety of respo...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693894/ https://www.ncbi.nlm.nih.gov/pubmed/17088286 http://dx.doi.org/10.1093/nar/gkl840 |