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Kinetic studies of HIV-1 and HIV-2 envelope glycoprotein-mediated fusion

BACKGROUND: HIV envelope glycoprotein (Env)-mediated fusion is driven by the concerted coalescence of the HIV gp41 N-helical and C-helical regions, which results in the formation of 6 helix bundles. Kinetics of HIV Env-mediated fusion is an important determinant of sensitivity to entry inhibitors an...

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Detalles Bibliográficos
Autores principales: Gallo, Stephen A, Reeves, Jacqueline D, Garg, Himanshu, Foley, Brian, Doms, Robert W, Blumenthal, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693918/
https://www.ncbi.nlm.nih.gov/pubmed/17144914
http://dx.doi.org/10.1186/1742-4690-3-90