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Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor

BACKGROUND: The urokinase-type (uPA) and tissue-type (tPA) plasminogen activators regulate liver matrix remodelling through the conversion of plasminogen (Plg) to the active protease plasmin. Based on the efficient activation of plasminogen when uPA is bound to its receptor (uPAR) and on the role of...

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Detalles Bibliográficos
Autores principales: Shanmukhappa, Kumar, Sabla, Gregg E, Degen, Jay L, Bezerra, Jorge A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1697812/
https://www.ncbi.nlm.nih.gov/pubmed/17134505
http://dx.doi.org/10.1186/1471-230X-6-40