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The strength of the HIV-1 3' splice sites affects Rev function

BACKGROUND: The HIV-1 Rev protein is a key component in the early to late switch in HIV-1 splicing from early intronless (e.g. tat, rev) to late intron-containing Rev-dependent (e.g. gag, vif, env) transcripts. Previous results suggested that cis-acting sequences and inefficient 5' and 3'...

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Detalles Bibliográficos
Autores principales: Kammler, Susanne, Otte, Marianne, Hauber, Ilona, Kjems, Jørgen, Hauber, Joachim, Schaal, Heiner
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1697824/
https://www.ncbi.nlm.nih.gov/pubmed/17144911
http://dx.doi.org/10.1186/1742-4690-3-89