Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter

BACKGROUND: Macrophages (Mθ) play a central role in the innate immune response and in the pathology of chronic inflammatory diseases. Macrophages treated with Th2-type cytokines such as Interleukin-4 (IL-4) and Interleukin-13 (IL-13) exhibit an altered phenotype and such alternatively activated macr...

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Detalles Bibliográficos
Autores principales: Liddiard, Kate, Welch, John S, Lozach, Jean, Heinz, Sven, Glass, Christopher K, Greaves, David R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698493/
https://www.ncbi.nlm.nih.gov/pubmed/17134490
http://dx.doi.org/10.1186/1471-2199-7-45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698493/
https://www.ncbi.nlm.nih.gov/pubmed/17134490
http://dx.doi.org/10.1186/1471-2199-7-45

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