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Integrated siRNA design based on surveying of features associated with high RNAi effectiveness

BACKGROUND: Short interfering RNAs have allowed the development of clean and easily regulated methods for disruption of gene expression. However, while these methods continue to grow in popularity, designing effective siRNA experiments can be challenging. The various existing siRNA design guidelines...

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Detalles Bibliográficos
Autores principales: Gong, Wuming, Ren, Yongliang, Xu, Qiqi, Wang, Yejun, Lin, Dong, Zhou, Haiyan, Li, Tongbin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698580/
https://www.ncbi.nlm.nih.gov/pubmed/17129386
http://dx.doi.org/10.1186/1471-2105-7-516