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Integrated siRNA design based on surveying of features associated with high RNAi effectiveness
BACKGROUND: Short interfering RNAs have allowed the development of clean and easily regulated methods for disruption of gene expression. However, while these methods continue to grow in popularity, designing effective siRNA experiments can be challenging. The various existing siRNA design guidelines...
Autores principales: | Gong, Wuming, Ren, Yongliang, Xu, Qiqi, Wang, Yejun, Lin, Dong, Zhou, Haiyan, Li, Tongbin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698580/ https://www.ncbi.nlm.nih.gov/pubmed/17129386 http://dx.doi.org/10.1186/1471-2105-7-516 |
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