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Elevated Serum Levels of Interferon-Regulated Chemokines Are Biomarkers for Active Human Systemic Lupus Erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder that affects multiple organ systems and is characterized by unpredictable flares of disease. Recent evidence indicates a role for type I interferon (IFN) in SLE pathogenesis; however, the downstream effects of I...

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Detalles Bibliográficos
Autores principales: Bauer, Jason W, Baechler, Emily C, Petri, Michelle, Batliwalla, Franak M, Crawford, Dianna, Ortmann, Ward A, Espe, Karl J, Li, Wentian, Patel, Dhavalkumar D, Gregersen, Peter K, Behrens, Timothy W
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702557/
https://www.ncbi.nlm.nih.gov/pubmed/17177599
http://dx.doi.org/10.1371/journal.pmed.0030491