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Why are mineralocorticoid receptor antagonists cardioprotective?
Two clinical trials, the Randomized ALdosterone Evaluation Study (RALES) and the EPlerenone HEart failure and SUrvival Study (EPHESUS), have recently shown that mineralocorticoid receptor (MR) antagonists reduce mortality in patients with heart failure on top of ACE inhibition. This effect could not...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705472/ https://www.ncbi.nlm.nih.gov/pubmed/17075718 http://dx.doi.org/10.1007/s00210-006-0107-9 |