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Why are mineralocorticoid receptor antagonists cardioprotective?

Two clinical trials, the Randomized ALdosterone Evaluation Study (RALES) and the EPlerenone HEart failure and SUrvival Study (EPHESUS), have recently shown that mineralocorticoid receptor (MR) antagonists reduce mortality in patients with heart failure on top of ACE inhibition. This effect could not...

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Detalles Bibliográficos
Autores principales: Chai, Wenxia, Danser, A. H. Jan
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705472/
https://www.ncbi.nlm.nih.gov/pubmed/17075718
http://dx.doi.org/10.1007/s00210-006-0107-9