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On-line optimization of glutamate production based on balanced metabolic control by RQ
In glutamate fermentations by Corynebacterium glutamicum, higher glutamate concentration could be achieved by constantly controlling dissolved oxygen concentration (DO) at a lower level; however, by-product lactate also severely accumulated. The results of analyzing activities changes of the two key...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705473/ https://www.ncbi.nlm.nih.gov/pubmed/16614826 http://dx.doi.org/10.1007/s00449-006-0059-y |