Cargando…

Dynamics of amino acid metabolism of primary human liver cells in 3D bioreactors

The kinetics of 18 amino acids, ammonia (NH3) and urea (UREA) in 18 liver cell bioreactor runs were analyzed and simulated by a two-compartment model consisting of a system of 42 differential equations. The model parameters, most of them representing enzymatic activities, were identified and their v...

Descripción completa

Detalles Bibliográficos
Autores principales: Guthke, R., Zeilinger, K., Sickinger, S., Schmidt-Heck, W., Buentemeyer, H., Iding, K., Lehmann, J., Pfaff, M., Pless, G., Gerlach, J.C.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705492/
https://www.ncbi.nlm.nih.gov/pubmed/16550345
http://dx.doi.org/10.1007/s00449-005-0040-1