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Dynamics of amino acid metabolism of primary human liver cells in 3D bioreactors
The kinetics of 18 amino acids, ammonia (NH3) and urea (UREA) in 18 liver cell bioreactor runs were analyzed and simulated by a two-compartment model consisting of a system of 42 differential equations. The model parameters, most of them representing enzymatic activities, were identified and their v...
Autores principales: | Guthke, R., Zeilinger, K., Sickinger, S., Schmidt-Heck, W., Buentemeyer, H., Iding, K., Lehmann, J., Pfaff, M., Pless, G., Gerlach, J.C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705492/ https://www.ncbi.nlm.nih.gov/pubmed/16550345 http://dx.doi.org/10.1007/s00449-005-0040-1 |
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