Gene transfer and expression in human neutrophils. The phox homology domain of p47(phox )translocates to the plasma membrane but not to the membrane of mature phagosomes

BACKGROUND: Neutrophils are non-dividing cells with poor survival after isolation. Consequently, exogenous gene expression in neutrophils is challenging. We report here the transfection of genes and expression of active proteins in human primary peripheral neutrophils using nucleofection. RESULTS: E...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Jennifer L, Ellis, Beverly A, Munafo, Daniela B, Brzezinska, Agnieszka A, Catz, Sergio D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1712351/
https://www.ncbi.nlm.nih.gov/pubmed/17150107
http://dx.doi.org/10.1186/1471-2172-7-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1712351/
https://www.ncbi.nlm.nih.gov/pubmed/17150107
http://dx.doi.org/10.1186/1471-2172-7-28

Ejemplares similares