Relationship of hypoxia-inducible factor 1α and p21(WAF1/CIP1 )expression to cell apoptosis and clinical outcome in patients with gastric cancer

BACKGROUND: Hypoxia-inducible factor-1α (HIF-1α) plays an essential role in oxygen homeostasis. The expression of HIF-1α-inducible genes is associated with tumor progression. p21 mediates cell cycle arrest and is one of the downstream genes targeted by HIF-1. PATIENTS AND METHODS: We examined the re...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizokami, Ken, Kakeji, Yoshihiro, Oda, Shinya, Maehara, Yoshihiko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716165/
https://www.ncbi.nlm.nih.gov/pubmed/17166265
http://dx.doi.org/10.1186/1477-7819-4-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716165/
https://www.ncbi.nlm.nih.gov/pubmed/17166265
http://dx.doi.org/10.1186/1477-7819-4-94

Ejemplares similares