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Relationship of hypoxia-inducible factor 1α and p21(WAF1/CIP1 )expression to cell apoptosis and clinical outcome in patients with gastric cancer
BACKGROUND: Hypoxia-inducible factor-1α (HIF-1α) plays an essential role in oxygen homeostasis. The expression of HIF-1α-inducible genes is associated with tumor progression. p21 mediates cell cycle arrest and is one of the downstream genes targeted by HIF-1. PATIENTS AND METHODS: We examined the re...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716165/ https://www.ncbi.nlm.nih.gov/pubmed/17166265 http://dx.doi.org/10.1186/1477-7819-4-94 |