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Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes

Selenocysteine (Sec) is cotranslationally inserted into protein in response to UGA codons and is the 21st amino acid in the genetic code. However, the means by which Sec is synthesized in eukaryotes is not known. Herein, comparative genomics and experimental analyses revealed that the mammalian Sec...

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Detalles Bibliográficos
Autores principales: Xu, Xue-Ming, Carlson, Bradley A, Mix, Heiko, Zhang, Yan, Saira, Kazima, Glass, Richard S, Berry, Marla J, Gladyshev, Vadim N, Hatfield, Dolph L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1717018/
https://www.ncbi.nlm.nih.gov/pubmed/17194211
http://dx.doi.org/10.1371/journal.pbio.0050004