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Polarised Asymmetric Inheritance of Accumulated Protein Damage in Higher Eukaryotes
Disease-associated misfolded proteins or proteins damaged due to cellular stress are generally disposed via the cellular protein quality-control system. However, under saturating conditions, misfolded proteins will aggregate. In higher eukaryotes, these aggregates can be transported to accumulate in...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1750924/ https://www.ncbi.nlm.nih.gov/pubmed/17147470 http://dx.doi.org/10.1371/journal.pbio.0040417 |