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Etomidate, pharmacological adrenalectomy and the critically ill: a matter of vital importance

Etomidate is a potent suppressant of adrenal steroidogenesis, effectively inducing reversible pharmacological adrenalectomy. Recent evidence suggests that for every five patients with septic shock given etomidate without corticosteroid supplementation, one patient will die as a consequence. Other cr...

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Detalles Bibliográficos
Autores principales: Bloomfield, Roxanna, Noble, David W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751005/
https://www.ncbi.nlm.nih.gov/pubmed/16941756
http://dx.doi.org/10.1186/cc5020