Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression

The Brn-3a and Brn-3b transcription factor have opposite and antagonistic effects in neuroblastoma cells since Brn-3a is associated with differentiation whilst Brn-3b enhances proliferation in these cells. In this study, we demonstrate that like Brn-3a, Brn-3b physically interacts with p53. However,...

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Detalles Bibliográficos
Autores principales: Budhram-Mahadeo, Vishwanie S., Bowen, Samantha, Lee, Sonia, Perez-Sanchez, Christina, Ensor, Elizabeth, Morris, Peter J., Latchman, David S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751550/
https://www.ncbi.nlm.nih.gov/pubmed/17145718
http://dx.doi.org/10.1093/nar/gkl878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751550/
https://www.ncbi.nlm.nih.gov/pubmed/17145718
http://dx.doi.org/10.1093/nar/gkl878

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