Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2′,5′-oligoadenylate synthetase from prostate cancer cells

The antiviral and antitumor functions of RNase L are enabled by binding to the allosteric effectors 5′-phosphorylated, 2′,5′-linked oligoadenylates (2-5A). 2-5A is produced by interferon-inducible 2′,5′-oligoadenylate synthetases (OAS) upon activation by viral double-stranded RNA (dsRNA). Because mu...

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Detalles Bibliográficos
Autores principales: Molinaro, Ross J., Jha, Babal Kant, Malathi, Krishnamurthy, Varambally, Sooryanarayana, Chinnaiyan, Arul M., Silverman, Robert H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751551/
https://www.ncbi.nlm.nih.gov/pubmed/17145707
http://dx.doi.org/10.1093/nar/gkl968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751551/
https://www.ncbi.nlm.nih.gov/pubmed/17145707
http://dx.doi.org/10.1093/nar/gkl968

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