A Role for Alström Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence

Premature truncation alleles in the ALMS1 gene are a frequent cause of human Alström syndrome. Alström syndrome is a rare disorder characterized by early obesity and sensory impairment, symptoms shared with other genetic diseases affecting proteins of the primary cilium. ALMS1 localizes to centrosom...

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Detalles Bibliográficos
Autores principales: Li, Guochun, Vega, Raquel, Nelms, Keats, Gekakis, Nicholas, Goodnow, Christopher, McNamara, Peter, Wu, Hua, Hong, Nancy A, Glynne, Richard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761047/
https://www.ncbi.nlm.nih.gov/pubmed/17206865
http://dx.doi.org/10.1371/journal.pgen.0030008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761047/
https://www.ncbi.nlm.nih.gov/pubmed/17206865
http://dx.doi.org/10.1371/journal.pgen.0030008

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