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Restricted epithelial proliferation by lacritin via PKCα-dependent NFAT and mTOR pathways
Renewal of nongermative epithelia is poorly understood. The novel mitogen “lacritin” is apically secreted by several nongermative epithelia. We tested 17 different cell types and discovered that lacritin is preferentially mitogenic or prosecretory for those types that normally contact lacritin durin...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761701/ https://www.ncbi.nlm.nih.gov/pubmed/16923831 http://dx.doi.org/10.1083/jcb.200605140 |