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Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy
BACKGROUND: Traditional multiplexed gene expression methods require well preserved, intact RNA. Such specimens are difficult to acquire in clinical practice where formalin fixation is the standard procedure for processing tissue. Even when special handling methods are used to obtain frozen tissue, t...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762006/ https://www.ncbi.nlm.nih.gov/pubmed/17144909 http://dx.doi.org/10.1186/1472-6890-6-9 |