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Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy

BACKGROUND: Traditional multiplexed gene expression methods require well preserved, intact RNA. Such specimens are difficult to acquire in clinical practice where formalin fixation is the standard procedure for processing tissue. Even when special handling methods are used to obtain frozen tissue, t...

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Detalles Bibliográficos
Autores principales: Haller, Andrew C, Kanakapalli, Deepa, Walter, Rosemarie, Alhasan, Samir, Eliason, James F, Everson, Richard B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762006/
https://www.ncbi.nlm.nih.gov/pubmed/17144909
http://dx.doi.org/10.1186/1472-6890-6-9