Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

BACKGROUND: Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are bioactive lipid signaling molecules implicated in tumor dissemination. Membrane-type matrix metalloproteinase 1 (MT1-MMP) is a membrane-tethered collagenase thought to be involved in tumor invasion via extracellular matrix...

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Detalles Bibliográficos
Autores principales: Fisher, Kevin E, Pop, Andreia, Koh, Wonshill, Anthis, Nicholas J, Saunders, W Brian, Davis, George E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762019/
https://www.ncbi.nlm.nih.gov/pubmed/17156449
http://dx.doi.org/10.1186/1476-4598-5-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762019/
https://www.ncbi.nlm.nih.gov/pubmed/17156449
http://dx.doi.org/10.1186/1476-4598-5-69

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