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Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

BACKGROUND: Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are bioactive lipid signaling molecules implicated in tumor dissemination. Membrane-type matrix metalloproteinase 1 (MT1-MMP) is a membrane-tethered collagenase thought to be involved in tumor invasion via extracellular matrix...

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Detalles Bibliográficos
Autores principales:	Fisher, Kevin E, Pop, Andreia, Koh, Wonshill, Anthis, Nicholas J, Saunders, W Brian, Davis, George E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762019/ https://www.ncbi.nlm.nih.gov/pubmed/17156449 http://dx.doi.org/10.1186/1476-4598-5-69

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