Experimental Rugged Fitness Landscape in Protein Sequence Space

The fitness landscape in sequence space determines the process of biomolecular evolution. To plot the fitness landscape of protein function, we carried out in vitro molecular evolution beginning with a defective fd phage carrying a random polypeptide of 139 amino acids in place of the g3p minor coat...

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Detalles Bibliográficos
Autores principales: Hayashi, Yuuki, Aita, Takuyo, Toyota, Hitoshi, Husimi, Yuzuru, Urabe, Itaru, Yomo, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762315/
https://www.ncbi.nlm.nih.gov/pubmed/17183728
http://dx.doi.org/10.1371/journal.pone.0000096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762315/
https://www.ncbi.nlm.nih.gov/pubmed/17183728
http://dx.doi.org/10.1371/journal.pone.0000096

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