Physiological Mouse Brain Aβ Levels Are Not Related to the Phosphorylation State of Threonine-668 of Alzheimer's APP

BACKGROUND: Amyloid-β peptide species ending at positions 40 and 42 (Aβ40, Αβ42) are generated by the proteolytic processing of the Alzheimer's amyloid precursor protein (APP). Aβ peptides accumulate in the brain early in the course of Alzheimer's disease (AD), especially Aβ42. The cytopla...

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Detalles Bibliográficos
Autores principales: Sano, Yoshitake, Nakaya, Tadashi, Pedrini, Steve, Takeda, Shizu, Iijima-Ando, Kanae, Iijima, Koichi, Mathews, Paul M., Itohara, Shigeyoshi, Gandy, Sam, Suzuki, Toshiharu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762327/
https://www.ncbi.nlm.nih.gov/pubmed/17183681
http://dx.doi.org/10.1371/journal.pone.0000051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762327/
https://www.ncbi.nlm.nih.gov/pubmed/17183681
http://dx.doi.org/10.1371/journal.pone.0000051

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