Cargando…
PIASγ Is Required for Faithful Chromosome Segregation in Human Cells
BACKGROUND: The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are removed and disjoined chromatids segregate to the spind...
Autores principales: | , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762334/ https://www.ncbi.nlm.nih.gov/pubmed/17183683 http://dx.doi.org/10.1371/journal.pone.0000053 |