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Cdx4 and Menin Co-Regulate Hoxa9 Expression in Hematopoietic Cells

BACKGROUND: Transcription factor Cdx4 and transcriptional coregulator menin are essential for Hoxa9 expression and normal hematopoiesis. However, the precise mechanism underlying Hoxa9 regulation is not clear. METHODS AND FINDINGS: Here, we show that the expression level of Hoxa9 is correlated with...

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Detalles Bibliográficos
Autores principales: Yan, Jizhou, Chen, Ya-Xiong, Desmond, Angela, Silva, Albert, Yang, Yuqing, Wang, Haoren, Hua, Xianxin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762371/
https://www.ncbi.nlm.nih.gov/pubmed/17183676
http://dx.doi.org/10.1371/journal.pone.0000047