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Catechol-O-Methyltransferase Gene Polymorphism Modifies the Effect of Coffee Intake on Incidence of Acute Coronary Events

BACKGROUND: The role of coffee intake as a risk factor for coronary heart disease (CHD) has been debated for decades. We examined whether the relationship between coffee intake and incidence of CHD events is dependent on the metabolism of circulating catecholamines, as determined by functional polym...

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Detalles Bibliográficos
Autores principales: Happonen, Pertti, Voutilainen, Sari, Tuomainen, Tomi-Pekka, Salonen, Jukka T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762420/
https://www.ncbi.nlm.nih.gov/pubmed/17205121
http://dx.doi.org/10.1371/journal.pone.0000117