Analysis of In-Vivo LacR-Mediated Gene Repression Based on the Mechanics of DNA Looping

Interactions of E. coli lac repressor (LacR) with a pair of operator sites on the same DNA molecule can lead to the formation of looped nucleoprotein complexes both in vitro and in vivo. As a major paradigm for loop-mediated gene regulation, parameters such as operator affinity and spacing, represso...

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Detalles Bibliográficos
Autores principales: Zhang, Yongli, McEwen, Abbye E., Crothers, Donald M., Levene, Stephen D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762422/
https://www.ncbi.nlm.nih.gov/pubmed/17205140
http://dx.doi.org/10.1371/journal.pone.0000136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762422/
https://www.ncbi.nlm.nih.gov/pubmed/17205140
http://dx.doi.org/10.1371/journal.pone.0000136

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