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DNA Encoding an HIV-1 Gag/Human Lysosome-Associated Membrane Protein-1 Chimera Elicits a Broad Cellular and Humoral Immune Response in Rhesus Macaques

Previous studies of HIV-1 p55Gag immunization of mice have demonstrated the usefulness of targeting antigens to the cellular compartment containing the major histocompatibility complex type II (MHC II) complex molecules by use of a DNA antigen formulation encoding Gag as a chimera with the mouse lys...

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Detalles Bibliográficos
Autores principales: Chikhlikar, Priya, de Arruda, Luciana Barros, Maciel, Milton, Silvera, Peter, Lewis, Mark G., August, J. Thomas, Marques, Ernesto T.A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762437/
https://www.ncbi.nlm.nih.gov/pubmed/17205139
http://dx.doi.org/10.1371/journal.pone.0000135