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Differential expression of type X collagen in a mechanically active 3-D chondrocyte culture system: a quantitative study

OBJECTIVE: Mechanical loading of cartilage influences chondrocyte metabolism and gene expression. The gene encoding type X collagen is expressed specifically by hypertrophic chondrocytes and up regulated during osteoarthritis. In this study we tested the hypothesis that the mechanical microenvironme...

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Detalles Bibliográficos
Autores principales: Yang, Xu, Vezeridis, Peter S, Nicholas, Brian, Crisco, Joseph J, Moore, Douglas C, Chen, Qian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764003/
https://www.ncbi.nlm.nih.gov/pubmed/17150098
http://dx.doi.org/10.1186/1749-799X-1-15