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The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA

BACKGROUND: Upon exposure to agents that damage DNA, Saccharomyces cerevisiae undergo widespread reprogramming of gene expression. Such a vast response may be due not only to damage to DNA but also damage to proteins, RNA, and lipids. Here the transcriptional response of S. cerevisiae specifically i...

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Detalles Bibliográficos
Autores principales: Fry, Rebecca C, DeMott, Michael S, Cosgrove, Joseph P, Begley, Thomas J, Samson, Leona D, Dedon, Peter C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764021/
https://www.ncbi.nlm.nih.gov/pubmed/17163986
http://dx.doi.org/10.1186/1471-2164-7-313