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Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome

BACKGROUND: The pattern of point mutation is important for studying mutational mechanisms, genome evolution, and diseases. Previous studies of mutation direction were largely based on substitution data from a limited number of loci. To date, there is no genome-wide analysis of mutation direction or...

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Detalles Bibliográficos
Autores principales: Jiang, Cizhong, Zhao, Zhongming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764022/
https://www.ncbi.nlm.nih.gov/pubmed/17166280
http://dx.doi.org/10.1186/1471-2164-7-316