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Selecting effective siRNA sequences by using radial basis function network and decision tree learning

BACKGROUND: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are only a few consistencies among the recently reported design rules/guidelines for selecting siRNA sequences effective for m...

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Detalles Bibliográficos
Autores principales: Takasaki, Shigeru, Kawamura, Yoshihiro, Konagaya, Akihiko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764479/
https://www.ncbi.nlm.nih.gov/pubmed/17254307
http://dx.doi.org/10.1186/1471-2105-7-S5-S22