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Metabolic design of macroscopic bioreaction models: application to Chinese hamster ovary cells
The aim of this paper is to present a systematic methodology to design macroscopic bioreaction models for cell cultures based upon metabolic networks. The cell culture is seen as a succession of phases. During each phase, a metabolic network represents the set of reactions occurring in the cell. The...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764600/ https://www.ncbi.nlm.nih.gov/pubmed/17013615 http://dx.doi.org/10.1007/s00449-006-0083-y |