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Multiple pathways contribute to the pathogenesis of Huntington disease

Huntington disease (HD) is caused by expansion of a polyglutamine (polyQ) domain in the protein known as huntingtin (htt), and the disease is characterized by selective neurodegeneration. Expansion of the polyQ domain is not exclusive to HD, but occurs in eight other inherited neurodegenerative diso...

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Detalles Bibliográficos
Autores principales: Li, Shihua, Li, Xiao-Jiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764744/
https://www.ncbi.nlm.nih.gov/pubmed/17173700
http://dx.doi.org/10.1186/1750-1326-1-19