Metabolic Fingerprints of Altered Brain Growth, Osmoregulation and Neurotransmission in a Rett Syndrome Model

BACKGROUND: Rett syndrome (RS) is the leading cause of profound mental retardation of genetic origin in girls. Since RS is mostly caused by mutations in the MECP2 gene, transgenic animal models such as the Mecp2-deleted (“Mecp2-null”) mouse have been employed to study neurological symptoms and brain...

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Detalles Bibliográficos
Autores principales: Viola, Angèle, Saywell, Véronique, Villard, Laurent, Cozzone, Patrick J., Lutz, Norbert W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766343/
https://www.ncbi.nlm.nih.gov/pubmed/17237885
http://dx.doi.org/10.1371/journal.pone.0000157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766343/
https://www.ncbi.nlm.nih.gov/pubmed/17237885
http://dx.doi.org/10.1371/journal.pone.0000157

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