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Impaired RNA incorporation and dimerization in live attenuated leader-variants of SIV(mac239)

BACKGROUND: The 5' untranslated region (UTR) or leader sequence of simian immunodeficiency virus (SIV(mac239)) is multifunctional and harbors the regulatory elements for viral replication, persistence, gene translation, expression, and the packaging and dimerization of viral genomic RNA (vRNA)....

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Detalles Bibliográficos
Autores principales: Whitney, James B, Wainberg, Mark A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766366/
https://www.ncbi.nlm.nih.gov/pubmed/17184529
http://dx.doi.org/10.1186/1742-4690-3-96