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Genome-Wide Reverse Genetics Framework to Identify Novel Functions of the Vertebrate Secretome

BACKGROUND: Understanding the functional role(s) of the more than 20,000 proteins of the vertebrate genome is a major next step in the post-genome era. The approximately 4,000 co-translationally translocated (CTT) proteins – representing the vertebrate secretome – are important for such vertebrate-c...

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Detalles Bibliográficos
Autores principales: Pickart, Michael A., Klee, Eric W., Nielsen, Aubrey L., Sivasubbu, Sridhar, Mendenhall, Eric M., Bill, Brent R., Chen, Eleanor, Eckfeldt, Craig E., Knowlton, Michelle, Robu, Mara E., Larson, Jon D., Deng, Yun, Schimmenti, Lisa A., Ellis, Lynda B.M., Verfaillie, Catherine M., Hammerschmidt, Matthias, Farber, Steven A., Ekker, Stephen C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766371/
https://www.ncbi.nlm.nih.gov/pubmed/17218990
http://dx.doi.org/10.1371/journal.pone.0000104