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Genome-Wide Reverse Genetics Framework to Identify Novel Functions of the Vertebrate Secretome
BACKGROUND: Understanding the functional role(s) of the more than 20,000 proteins of the vertebrate genome is a major next step in the post-genome era. The approximately 4,000 co-translationally translocated (CTT) proteins – representing the vertebrate secretome – are important for such vertebrate-c...
Autores principales: | Pickart, Michael A., Klee, Eric W., Nielsen, Aubrey L., Sivasubbu, Sridhar, Mendenhall, Eric M., Bill, Brent R., Chen, Eleanor, Eckfeldt, Craig E., Knowlton, Michelle, Robu, Mara E., Larson, Jon D., Deng, Yun, Schimmenti, Lisa A., Ellis, Lynda B.M., Verfaillie, Catherine M., Hammerschmidt, Matthias, Farber, Steven A., Ekker, Stephen C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766371/ https://www.ncbi.nlm.nih.gov/pubmed/17218990 http://dx.doi.org/10.1371/journal.pone.0000104 |
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