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Evx2-Hoxd13 Intergenic Region Restricts Enhancer Association to Hoxd13 Promoter

Expression of Hox genes is tightly regulated in spatial and temporal domains. Evx2 is located next to Hoxd13 within 8 kb on the opposite DNA strand. Early in development, the pattern of Hoxd13 expression resembles that of Evx2 in limb and genital buds. After 10 dpc, however, Evx2 begins to be expres...

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Detalles Bibliográficos
Autores principales: Yamagishi, Takumi, Ozawa, Michiru, Ohtsuka, Chiho, Ohyama-Goto, Ritsuko, Kondo, Takashi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766471/
https://www.ncbi.nlm.nih.gov/pubmed/17245451
http://dx.doi.org/10.1371/journal.pone.0000175