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Mariner mutagenesis of Brucella melitensis reveals genes with previously uncharacterized roles in virulence and survival

BACKGROUND: Random gene inactivation used to identify cellular functions associated with virulence and survival of Brucella spp has relied heavily upon the use of the transposon Tn5 that integrates at G/C base pairs. Transposons of the mariner family do not require species-specific host factors for...

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Detalles Bibliográficos
Autores principales: Wu, Qingmin, Pei, Jianwu, Turse, Carol, Ficht, Thomas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766931/
https://www.ncbi.nlm.nih.gov/pubmed/17176467
http://dx.doi.org/10.1186/1471-2180-6-102