Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell

We present evidence that variations in cyclin D1 levels through the cell cycle are essential for continuing proliferation. Cyclin D1 levels must be high during G1 phase for a cell to initiate DNA synthesis, but then must be suppressed to low levels during S phase to allow for efficient DNA synthesis...

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Detalles Bibliográficos
Autores principales: Yang, Ke, Hitomi, Masahiro, Stacey, Dennis W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769361/
https://www.ncbi.nlm.nih.gov/pubmed/17176475
http://dx.doi.org/10.1186/1747-1028-1-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769361/
https://www.ncbi.nlm.nih.gov/pubmed/17176475
http://dx.doi.org/10.1186/1747-1028-1-32

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